I was getting lost in familiar places, having panic attacks over small decisions like what to wear, struggling with word recall, unable to learn new skills, and emotionally volatile. I took rivastigmine transdermal 4.6mg for 6 months and it's almost completely gone now. I still get some flareups of brain fog associated with MCAS but I don't feel like I have dementia anymore, and my moods are much stabler. It didn't feel like it was doing anything until around month 5, but the results were astonishing and permanent.

It significantly improved my tachycardia, lightheade­dness upon standing up, hypoglycemia, and cold/heat intolerance. It also really helped my MCAS. It does cause significant bronchial secretions so I always feel like I'm coming down with a chest cold, but I've managed to tune it out.

I did nebulized budesonide 2x/d for 3 months in a Long Covid clinic a few years back. It took time, but it significantly and permanently helped my short term memory loss, anxiety, and indecisiveness. I didn't have any side effects from it. The only downside is that it's pretty time consuming, but it was well worth it.

NAC profoundly and rapidly improved my fatigue (ME/CFS). It worked fantastically for about a year for me. But around one year, I started getting really bad histamine intolerance symptoms, which got pushed over the edge after I switched to a more potent brand of NAC. The last few times I tried to take NAC, I had really severe neurological symptoms from histamine intolerance. Given how sensitive people with LC are to histamine intolerance and mast cell disease, I wouldn't recommend anyone take it long term. Maybe taking it in cycles would be safer.

I took 500mg/d for one week with 2-4 weeks off. It helped a bit with fatigue, particularly my severe morning drowsiness. If I took it for longer than 7 days, I would get very sluggish, although it would go away within 24 hours of stopping metformin. I made up this dosing schedule. I noticed it would start backfiring around the one week mark, so I'd stop and then re-start once the morning drowsiness came back, which was usually a few weeks. Unfortunately, around 4 months into using it in these cycles, I started having severe nausea and stomach pain. Felt like digesting razorblades. I couldn't mitigate it by taking it with/out food or at different times, so I just stopped.