Long COVID Acronyms

The following is a list of acronyms commonly used by people with Long COVID:

Acronym Term Description

CBC

Complete Blood Count

A lab test frequently ordered for people with Long COVID to assess overall health and detect abnormalities such as anemia or infections that may contribute to fatigue and other symptoms.

CFS

Chronic Fatigue Syndrome

An alternative name for Myalgic Encephalomyelitis (ME), often used interchangeably. Both conditions are characterized by debilitating fatigue, post-exertional malaise (PEM), and other overlapping symptoms.

CMP

Comprehensive Metabolic Panel

A blood test frequently ordered for Long COVID patients to check for electrolyte imbalances, kidney function, and liver health, which can be impacted by the condition.

CRP

C-Reactive Protein

A marker of inflammation commonly tested in people with Long COVID. Elevated levels may indicate ongoing inflammation or an immune response contributing to symptoms.

EBV

Epstein-Barr Virus A virus that can reactivate in people with Long COVID, potentially contributing to symptoms such as fatigue and neurological issues.

HR

Heart Rate Long COVID patients often monitor their heart rate using wearable devices to manage symptoms like dysautonomia and avoid post-exertional malaise (PEM).

HRV

Heart Rate Variability A measure of the variation in time between heartbeats. Monitoring HRV can help individuals with Long COVID assess their autonomic nervous system function and manage symptoms.

IVIG

Intravenous immunoglobulin A treatment involving the infusion of antibodies from healthy donors. It is used to treat autoimmune disorders and small fiber neuropathy (SFN), both of which can occur in Long COVID patients.

IVM

Ivermectin An anti-parasitic drug. While controversial, some have advocated for its use in treating acute COVID and Long COVID symptoms.

LC

Long COVID An umbrella term that encompasses the many different health problems experienced after the acute phase of a COVID-19 infection.

LDN

Low Dose Naltrexone Some Long COVID patients use this medication in small doses (0.5-10mg) to reduce inflammation and manage symptoms. It is typically prescribed for other conditions in much higher doses.

MCAS

Mast Cell Activation Syndrome A disorder where mast cells release excessive chemicals into the body, causing symptoms like allergic reactions, rashes, and gastrointestinal issues. Many people with Long COVID report MCAS symptoms.

ME

Myalgic Encephalomyelitis A chronic illness with symptoms that often overlap with Long COVID, including profound fatigue, post-exertional malaise (PEM), unrefreshing sleep, and cognitive impairment.

ME/CFS

Myalgic Encephalomyelitis / Chronic Fatigue Syndrome A combined term to reduce confusion and acknowledge the overlap between ME and CFS diagnoses.

NAC

N-Acetylcysteine A supplement that acts as a precursor to glutathione, a key antioxidant. Some Long COVID patients use it to reduce oxidative stress and improve respiratory function.

NAD+

Nicotinamide Adenine Dinucleotide 

A coenzyme essential for cellular energy production. Some Long COVID patients take NAD+ or its precursors to address fatigue and support mitochondrial function.

OTS

Orthostatic Intolerance A condition where standing leads to symptoms such as dizziness, lightheadedness, or fainting, often seen in people with Long COVID due to dysautonomia.

PASC

Post-Acute Sequelae of COVID A formal medical term for Long COVID, commonly used in research and clinical settings.

PEM

Post-exertional Malaise A hallmark symptom of Long COVID where physical or mental exertion worsens symptoms, often leading to what patients describe as a “crash.”

POTS

Postural Orthostatic Tachycardia Syndrome Many Long COVID patients develop this syndrome, which is characterized by an abnormal increase in heart rate upon standing, leading to symptoms like lightheadedness and fatigue.

PRP

Platelet-Rich Plasma A treatment where a patient’s blood is processed to concentrate platelets rich in growth factors. Some Long COVID patients use PRP to treat lingering symptoms.

SFN

Small Fiber Neuropathy A condition involving damage to small nerve fibers, causing pain, tingling, or burning sensations, often seen in Long COVID patients.

SGB

Stellate Ganglion Block A procedure where a local anesthetic is injected into the nerves of the neck. Some Long COVID patients report symptom improvement after undergoing SGB.

SOB

Shortness of Breath A common symptom in Long COVID, often linked to respiratory or cardiovascular issues.